Ant acrids- Neutralize stomach acids
-Aluminum Salts- constipating effects, often apply w/ magnesium to counteract, often used with patients with renal distemper (easily excreted)
-Magnesium salts- commonly develop diarrhea
-Calcium salts- whitethorn cause constipation and kidney stones, desire duration of acid action,
-Sodium Bicarbonate- quick onset, short duration. May cause metabolic alkalosis, sodium content may cause problems w/ patients w/ HF hypertension
Give meds 1-2 hours after antacid
Antiflatulents- drugs: Simethicone, Activated Charcoal
H2 Antagonists- bowdlerize acid secretion
Cimetidine (Tagament)- Binds with P-450, resulting in increased drug levels
ranitidine (Zantac)
Smoking decreases effectiveness of h2 blockers
Proton Pump Inhibitors- achlorhydriaâ€"ALL gastric acid secretion is temporarily blocked
Used for GERD maintenance therapy, Erosive esophagitis, short-term treatment of active duodenal and benign gastric ulcers, Zollinger-Ellison syndrome, manipulation of H. pyloriinduced ulcers.
Proton pump inhibitors often work best when taken 30 to 60 minutes before meals
Omeprazole (Prilosec)
Pantoprazole (Protonix)- specifically indicated treatment of h pylori, may increase bleeding with warfarin.
other drugs:
Sucralfate (Carafate)- forming a protective barrier over ulcers, demo other drugs at least 2 hours before sucralfate, may be used in chronic renal bereavement to reduce phosphate levels
Misoprostol (Cytotec)- Used for prevention of NSAID-induced gastric ulcers, value gastric mucosa from injury by enhancing local end product of mucus
Ch 51- Bowel Disorder Drugs
Antidiarrheals-
-Adsorbents: Coat walls of GI tract, bind to responsible bacteria or toxin then eliminated through stool. Examples: bismuth subsalicylate (Pepto-Bismol). change magnitude bleeding time. Blue Gums, Tinnitis, hearing loss, dark stools. Decreased engrossment of digoxin, clindamycin, quinidine, hypoglycemic drugs. NO PEPTO BISMOL TO...If you want to get a encompassing essay, order it on our website: Orderessay
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